The Red Devils are already nine points adrift of the top four and today's game is a must-win to avoid losing further ground in the Champions League hunt.

Formation: 3-4-2-1

Predicted Line-up:

Andre Onana has made high-profile mistakes in goal in the last two games, but he is expected to continue between the sticks for the Manchester derby.

The defence should see one change. Leny Yoro is set to be reinstated into the starting XI alongside Matthijs de Ligt and Lisandro Martinez .

Amad Diallo is likely to drop into the right wing-back role, having played as a no.10 in midweek. Diogo Dalot should drop to the bench.

Similarly, Tyrell Malacia could make way for Noussair Mazraoui at left wing-back. Mazraoui is better equipped to handle City's attacking threat.

In midfield, Casemiro and Manuel Ugarte could be paired alongside each other. The former was fantastic against Viktoria Plzen with 100 percent ground duels won.

Bruno Fernandes could be accompanied by Mason Mount in the attacking midfield positions. Rasmus Hojlund is set to lead the line after his brace in midweek.

Predicted Man Utd line-up (3-4-2-1) vs Man City : Onana; Yoro, De Ligt, Martinez; Diallo, Casemiro, Ugarte, Mazraoui; Fernandes, Mount; Hojlund.

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